Endocrine Abstracts

Tissue engineering is a new discipline that capitalizes on the expertise of cell biologists and material scientists. It attempts to create three-dimensional complexes of cells and scaffolds for the purposes of repair, regeneration or replacement of diseased tissue. The tissues and organs are constructed using appropriate cells, genes or other biological building blocks along with bioengineered materials and technologies There is no clear evidence yet as to the most appropriate...

Introduction: Trisomy 21 or Down Syndrome (DS) patients have a predisposition for Congenital Hypothyroidism which can aggravate their mental status.Hypothesis: The presence of three copy of Dyrk1a gene, localized in chromosome 21 in Humans, is responsible for a thyroidal dysgenesis.Our aim is to understand the molecular mechanisms underlying this condition.Methods: The transgenic Dyrk1a (TgDyrk1a) mouse, our ...